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Product Overview

The Genova is an efficient, high performance grating spectrophotometer designed for the busy molecular biologist. With RNA/DNA, oligonucleotide, protein and O.D. analysis software on board, results can be obtained quickly and accurately. In addition, the Genova is extremely versatile offering method storage, photometric operation, a selectable wavelength range of 198 to 1000nm, and scanning capabilities for purity. The on board software has in permanent memory, the wavelengths, calculations and factors necessary for analysis including the following: Protein: Bradford, Lowry, Biuret, Biccinchonic, and direct UV 260/280 ratio and 260/230 ratio with correction by subtraction at a third wavelength and multiplication by factors ssDNA, dsDNA, RNA, Oligonucleotides and OD 600.  Also, a variable ratio mode allows the user to change the wavelengths and factors allowing for fine adjustment and greater accuracy. Optimized for low volume analysis the determination of DNA levels as low as 70ng with sample volumes as low as 50µl is possible using the 50ul masked quartz cuvette. This lightweight, compact analyzer can fit easily anywhere in the lab, while the 5-button keypad and the large LCD allow for effortless interfacing. The Genova self-calibrates at 3 wavelengths, assuring optimal operation every time it is turned on. With a single touch of the print key, results and G.L.P. compliant information can be printed or transferred to a PC, through the RS232 port. The Genova features a xenon lamp, which has the advantage of offering a broad spectral source with high-energy light throughout the wavelength range. The xenon lamp flashes at a high rate, extending lamp life and lowering operation costs. This innovative laboratory instrument is covered under a 3-year warranty*, and is priced to fit any laboratory budget.  * The Xenon lamp is warranted for 12 months

Photometrics Mode  

This operation mode can be used for routine analysis of samples and features:

                       

·                Wavelength selection over the entire wavelength range of 198nm-1000nm

·                Simultaneous quad-display of Concentration, Absorbance, % Transmittance, and Wavelength 

for easy direct reading

·                Selectable Concentration units, for greater versatility including: m g/ml, mg/l, g/l, mg/l, ppm, mM,

M, %, ng/ml, mg/ml or can be left blank

 

On-board RNA/DNA Analytical Software

Stored in the permanent memory are the wavelengths, calculations and factors necessary for analysis of proteins, DNA/RNA, and oligonucleotides. Corrections can be made by subtraction at a third wavelength and multiplication by factors. A variable ratio mode allows the user to change the wavelengths and factors allowing for fine adjustment and greater accuracy. The Genova is also ideal for OD 600 bacterial measurements.

 

On-board Protein Analytical Software

Protein methods include Bradford, Lowry, Biuret, Biccinchonic, and direct UV methods. Measurement is by standard curve and can be accomplished by calibration of up to 6 standard solutions or by manual entry. The curve can be viewed as a graphic or as a data list, while statistics show the terms used for the calculated quadratic curve fit. When analyzing an unknown sample against the curve, a tri-display of wavelength, concentration and absorbencies is easily read on the large LCD. The protein software also features a direct UV mode that does not use a calibration curve, but utilizes readings at 280nm and 260nm.

 

Method Storage

Allows the user to save up to 10 protein calibration curve methods, for easy recall. The method settings and the last date and time the method was modified are simultaneously displayed.

 

Purity Scans

This mode allows a user to optimize measurements by zeroing in on peak absorbance wavelengths. Scans can be performed over the entire wavelength range of 198 to 1000nm, in increments of 100nm at 1nm intervals. An easy to read graphical representation of absorbance versus wavelength is displayed, with a final statistical display of peak absorbance and wavelength. A hard copy printout can be obtained by one touch of the print key.

 

RS232 and Analogue Outputs

The RS232 port allows the user to print data out directly or download data to a PC through HyperTerminal with a single touch of the print key. 

 

Security Lock

The instrument lock mechanism prevents operating parameters of the unit from being changed and is protected by a three digit locking code.

 

Self-Calibration

Upon startup, a self-calibration test is performed at 3-wavelengths, 247nm, 528nm, and 824nm to ensure G.L.P. (Good Laboratory Practice) compliant operation. If the unit does not pass the test, a message will be displayed.

 

Versatile Sampling System

The Genova is standard with a 10 x 10mm cuvette holder. Accessories can be easily interchanged and include:

·                Sipper system

·                4-positon cell holder

·                Test tube holders that hold 13mm, 25mm, and 16mm tubes

·                20-100mm cell holder

 

          Small Footprint

The unit is only 10.3 inches wide, 7.6 inches deep, 4.5 inches high, and weighs only 13 pounds. It saves valuable bench space and can be easily moved around the lab or a department.

 

Xenon Lamp

The xenon lamp is a long lasting, high-energy lamp that is covered by a one year warranty.